I don't see any indication that DNSSEC would have been relevant there? Their assessment was that that interception (and certificate issuance) were completed by redirecting traffic for the legitimate IPs to another destination. The DNS records continued to work as expected.
> real world compromises of major sites that don't use DNSSEC?
Without any other changes to this infrastructure DNSSEC by itself wouldn't have prevented this, but it could have been combined with something else like a CAA record.
Given the large amount of sites, including popular sites, that do not have DNSSEC today, I'd expect that if this was a real risk we'd see a decent number of instances where it occurred.
And yet I see zero. Is it possible that given other mitigations (like multi-perspective validation) and given other attack vectors (like account takeover), this isn't actually a problem?